CDC HIV/AIDS Surveillance Report, First Quarter 1993 U.S. AIDS Cases Reported Through March 1993 Online Edition: Issued June 23, 1993 ========================================================================= This issue of the Report initiates the following: 1) three months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents are included in the report; 2) Table 2 uses revised Metropolitan Statistical Area definitions issued in December 1992; 3) several tables and figures have been expanded to provide separate tabulations for adult/adolescent males and females and to provide additional tabulations for the most recent 12-month period; and 4) volume and issue numbers have been added to the title page. See technical notes for additional information. REPORT DESCRIPTION: The U.S. AIDS case data presented below are extracted from the "HIV/AIDS Surveillance Report", published each quarter by the Division of HIV/AIDS, Center for Infectious Diseases, Centers for Disease Control, and Prevention Atlanta, GA 30333. In addition to the data presented here, the printed report contains maps, figures, and technical notes. Single copies of the year-end edition printed report are available free from: CDC National AIDS Clearinghouse P.O. Box 6003 Rockville, MD 20849-6003 1-800-458-5231 1-800-243-7012 TTY/TDD 1-301-738-6616 FAX Individuals or organizations may also request to be added to the Surveillance Report mailing list. ========================================================================= Table 1. AIDS cases and annual rates per 100,000 population, by state, reported April 1991 through March 1992, April 1992 through March 1993 (1); and cumulative totals through March 1993 (2) Apr. 1991- Apr. 1992- Mar. 1992 Mar. 1993 State of residence No. Rate No. Rate Alabama 404 9.9 667 16.1 Alaska 22 3.9 15 2.5 Arizona 312 8.3 1,080 28.2 Arkansas 199 8.4 415 17.3 California 8,501 28.0 12,916 41.7 Colorado 439 13.0 1,010 29.2 Connecticut 542 16.5 868 26.3 Delaware 88 12.9 266 38.3 District of Columbia 738 123.3 895 151.8 Florida 5,590 42.1 7,655 56.2 Georgia 1,470 22.2 2,277 33.6 Hawaii 191 16.8 105 9.0 Idaho 34 3.3 62 5.8 Illinois 1,681 14.6 2,392 20.5 Indiana 404 7.2 531 9.4 Iowa 96 3.4 204 7.3 Kansas 165 6.6 306 12.2 Kentucky 161 4.3 246 6.6 Louisiana 882 20.7 914 21.3 Maine 56 4.5 77 6.2 Maryland 997 20.5 1,521 30.8 Massachusetts 969 16.2 1,443 24.1 Michigan 816 8.7 1,212 12.8 Minnesota 197 4.4 520 11.6 Mississippi 212 8.2 341 13.1 Missouri 685 13.3 1,709 32.9 Montana 25 3.1 31 3.8 Nebraska 63 4.0 135 8.4 Nevada 247 19.2 442 32.4 New Hampshire 47 4.3 89 8.1 New Jersey 2,318 29.9 2,910 37.4 New Mexico 111 7.2 269 17.0 New York 7,731 42.8 11,032 60.9 North Carolina 616 9.1 713 10.4 North Dakota 1 0.2 4 0.6 Ohio 663 6.1 951 8.6 Oklahoma 256 8.1 593 18.5 Oregon 287 9.8 629 21.0 Pennsylvania 1,214 10.1 1,674 13.9 Rhode Island 101 10.1 164 16.3 South Carolina 374 10.5 862 23.7 South Dakota 7 1.0 23 3.2 Tennessee 393 7.9 681 13.5 Texas 3,210 18.5 5,482 31.0 Utah 146 8.2 264 14.5 Vermont 17 3.0 31 5.4 Virginia 627 10.0 1,201 18.8 Washington 591 11.8 563 10.9 West Virginia 69 3.8 47 2.6 Wisconsin 207 4.2 234 4.7 Wyoming 12 2.6 33 7.1 U.S. total 45,184 17.9 68,704 26.9 Guam 2 1.5 2 1.5 Pacific Islands, U.S. - - 1 0.9 Puerto Rico 1,414 39.8 2,447 68.2 Virgin Islands, U.S. 22 21.5 42 40.8 Total 46,622 18.2 71,196 27.4 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 During the first quarter of 1993, 35,779 cases and 11,471 deaths among adults/adolescents and 219 cases and 103 deaths among children were reported to CDC. Table 1. AIDS cases and annual rates per 100,000 population, by state, reported April 1991 through March 1992, April 1992 through March 1993 (1); and cumulative totals through March 1993 (2) -- continued Cumulative Totals -------------------------------------- State of residence Adults Children adolescents < 13 years old Total Alabama 2,013 43 2,056 Alaska 136 3 139 Arizona 2,704 13 2,717 Arkansas 1,093 18 1,111 California 53,516 335 53,851 Colorado 3,143 19 3,162 Connecticut 3,330 91 3,421 Delaware 681 7 688 District of Columbia 4,403 69 4,472 Florida 27,692 684 28,376 Georgia 8,261 80 8,341 Hawaii 967 7 974 Idaho 178 2 180 Illinois 8,970 122 9,092 Indiana 2,010 15 2,025 Iowa 539 5 544 Kansas 934 5 939 Kentucky 953 12 965 Louisiana 4,215 61 4,276 Maine 362 2 364 Maryland 5,757 132 5,889 Massachusetts 5,872 112 5,984 Michigan 4,121 61 4,182 Minnesota 1,574 12 1,586 Mississippi 1,261 20 1,281 Missouri 4,349 31 4,380 Montana 116 1 117 Nebraska 394 3 397 Nevada 1,366 13 1,379 New Hampshire 337 6 343 New Jersey 15,759 412 16,171 New Mexico 751 2 753 New York 53,962 1,192 55,154 North Carolina 3,034 72 3,106 North Dakota 29 0 29 Ohio 4,080 61 4,141 Oklahoma 1,573 15 1,588 Oregon 1,978 9 1,987 Pennsylvania 7,519 111 7,630 Rhode Island 649 9 658 South Carolina 2,342 32 2,374 South Dakota 53 2 55 Tennessee 2,229 22 2,251 Texas 20,462 200 20,662 Utah 752 16 768 Vermont 127 2 129 Virginia 4,009 75 4,084 Washington 3,538 18 3,556 West Virginia 301 4 305 Wisconsin 1,124 11 1,135 Wyoming 87 0 87 U.S. total 275,605 4,249 279,854 Guam 12 0 12 Pacific Islands, U.S. 3 0 3 Puerto Rico 9,081 226 9,307 Virgin Islands, U.S. 139 5 144 U.S. total 284,840 4,480 289,320 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 During March 1993, 35,779 cases and 11,471 deaths among adults/adolescents and 219 cases and 103 deaths among children were reported to CDC. ========================================================================= Table 2. AIDS cases by metropolitan area, reported in March 1993; cases and rates per 100,000 population by metropolitan area with 500,000 or more population, reported April 1991 through March 1992, and April 1992 through March 1993 (1); and cumulative totals, by area and age group, through March 1993 Apr. 1991- Apr. 1992- Mar. 1992 Mar. 1993 Metropolitan area of residence (2) No. Rate No. Rate Akron, Ohio 36 5.4 42 6.3 Albany-Schenectady, N.Y. 91 10.5 108 12.3 Albuquerque, N.M. 69 11.5 163 26.5 Allentown, Pa. 33 5.5 58 9.5 Ann Arbor, Mich. 38 7.6 37 7.3 Atlanta, Ga. 1,093 35.8 1,547 49.2 Austin, Tex. 225 25.7 462 51.2 Bakersfield, Calif. 61 10.8 71 12.0 Baltimore, Md. 561 23.2 971 39.7 Birmingham, Ala. 115 13.5 207 24.1 Boston, Mass. 854 15.1 1,238 22.0 Buffalo, N.Y. 98 8.2 72 6.0 Charleston, S.C. 78 14.9 176 32.6 Charlotte, N.C. 100 8.4 146 12.0 Chicago, Ill. 1,461 19.5 2,094 27.6 Cincinnati, Ohio 112 7.3 148 9.5 Cleveland, Ohio 206 9.3 291 13.1 Columbus, Ohio 123 9.0 197 14.1 Dallas, Tex. 818 29.9 1,574 56.2 Dayton, Ohio 65 6.8 84 8.7 Denver, Colo. 368 22.1 838 48.9 Detroit, Mich. 625 14.6 793 18.4 El Paso, Tex. 31 5.1 77 12.2 Fort Lauderdale, Fla. 938 72.9 906 68.7 Fort Worth, Tex. 192 13.8 237 16.6 Fresno, Calif. 79 10.1 112 13.9 Gary, Ind. 39 6.4 52 8.4 Grand Rapids, Mich. 50 5.2 101 10.4 Greensboro, N.C. 114 10.7 120 11.1 Greenville, S.C. 47 5.6 169 19.8 Harrisburg, Pa. 43 7.2 56 9.3 Hartford, Conn. 163 14.5 342 30.4 Honolulu, Hawaii 138 16.2 82 9.5 Houston, Tex. 1,183 34.4 2,019 56.8 Indianapolis, Ind. 196 13.9 224 15.7 Jacksonville, Fla. 270 28.9 863 89.8 Kansas City, Mo. 276 17.2 753 46.4 Knoxville, Tenn. 35 5.8 39 6.4 Las Vegas, Nev. 195 21.1 342 34.3 Little Rock, Ark. 70 13.5 172 32.8 Los Angeles, Calif. 3,130 34.9 4,344 47.8 Louisville, Ky. 81 8.5 112 11.6 Memphis, Tenn. 129 12.6 260 25.2 Miami, Fla. 1,976 100.0 1,707 84.6 Milwaukee, Wis. 107 7.4 130 8.9 Minneapolis-Saint Paul, Minn. 169 6.5 459 17.5 Nashville, Tenn. 120 12.0 212 20.8 New Haven, Conn. 338 20.7 463 28.3 New Orleans, La. 518 40.0 467 35.8 New York, N.Y. (3) 8,947 52.7 12,669 74.5 Bergen-Passaic, N.J. 268 20.9 346 27.0 Jersey City, N.J. 434 78.4 344 62.1 Middlesex, N.J. 199 19.4 285 27.6 Monmouth-Ocean City, N.J. 141 14.2 278 27.6 Nassau-Suffolk, N.Y. 306 11.7 398 15.1 Newark, N.J. 956 52.5 1,084 59.6 New York, N.Y. (1983 MSA definition) 6,641 77.7 9,921 115.9 Norfolk, Va. 133 9.1 248 16.7 Oakland, Calif. 481 22.8 1,027 48.0 Oklahoma City, Okla. 103 10.6 278 28.3 Omaha, Neb. 46 7.1 104 15.8 Orange County, Calif. 645 26.4 429 17.3 Orlando, Fla. 391 30.8 838 63.8 Philadelphia, Pa. 934 18.9 1,293 26.1 Phoenix, Ariz. 237 10.4 843 36.1 Table 2. AIDS cases by metropolitan area, reported in March 1993; cases and rates per 100,000 population by metropolitan area with 500,000 or more population, reported April 1991 through March 1992, and April 1992 through March 1993 (1); and cumulative totals, by area and age group, through March 1993 - continued Cumulative Totals --------------------------------------- Metropolitan Adults/ Children area of residence adolescents < 13 years old Total Akron, Ohio 195 - 195 Albany-Schenectady, N.Y. 506 12 518 Albuquerque, N.M. 441 1 442 Allentown, Pa. 236 4 240 Ann Arbor, Mich. 157 4 161 Atlanta, Ga. 6,135 39 6,174 Austin, Tex. 1,452 13 1,465 Bakersfield, Calif. 249 3 252 Baltimore, Md. 3,499 104 3,603 Birmingham, Ala. 615 11 626 Boston, Mass. 5,252 97 5,349 Buffalo, N.Y. 493 5 498 Charleston, S.C. 501 3 504 Charlotte, N.C. 582 9 591 Chicago, Ill. 7,914 109 8,023 Cincinnati, Ohio 646 9 655 Cleveland, Ohio 1,152 23 1,175 Columbus, Ohio 862 6 868 Dallas, Tex. 5,258 24 5,282 Dayton, Ohio 403 8 411 Denver, Colo. 2,595 14 2,609 Detroit, Mich. 2,872 45 2,917 El Paso, Tex. 241 1 242 Fort Lauderdale, Fla. 4,469 103 4,572 Fort Worth, Tex. 1,094 12 1,106 Fresno, Calif. 407 4 411 Gary, Ind. 192 1 193 Grand Rapids, Mich. 290 2 292 Greensboro, N.C. 520 11 531 Greenville, S.C. 391 1 392 Harrisburg, Pa. 269 6 275 Hartford, Conn. 1,087 18 1,105 Honolulu, Hawaii 725 5 730 Houston, Tex. 8,181 80 8,261 Indianapolis, Ind. 949 4 953 Jacksonville, Fla. 1,910 50 1,960 Kansas City, Mo. 2,065 7 2,072 Knoxville, Tenn. 184 2 186 Las Vegas, Nev. 1,053 13 1,066 Little Rock, Ark. 437 8 445 Los Angeles, Calif. 18,760 140 18,900 Louisville, Ky. 406 7 413 Memphis, Tenn. 763 6 769 Miami, Fla. 8,061 234 8,295 Milwaukee, Wis. 614 7 621 Minneapolis-Saint Paul, Minn. 1,398 9 1,407 Nashville, Tenn. 717 9 726 New Haven, Conn. 1,981 70 2,051 New Orleans, La. 2,534 34 2,568 New York, N.Y. (3) 63,021 1,495 64,516 Bergen-Passaic, N.J. 1,982 50 2,032 Jersey City, N.J. 2,556 69 2,625 Middlesex, N.J. 1,337 30 1,367 Monmouth-Ocean City, N.J. 1,108 33 1,141 Nassau-Suffolk, N.Y. 2,376 60 2,436 Newark, N.J. 6,429 179 6,608 New York, N.Y. (1983 def.) 47,188 1,071 48,259 Norfolk, Va. 865 22 887 Oakland, Calif. 3,691 25 3,716 Oklahoma City, Okla. 745 1 746 Omaha, Neb. 287 1 288 Orange County, Calif. 2,438 16 2,454 Orlando, Fla. 2,060 37 2,097 Philadelphia, Pa. 5,760 77 5,837 Phoenix, Ariz. 2,045 9 2,054 Table 2. AIDS cases by metropolitan area, reported in March 1993; cases and rates per 100,000 population by metropolitan area with 500,000 or more population, reported April 1991 through March 1992, and April 1992 through March 1993 (1); and cumulative totals, by area and age group, through March 1993 - Continued Apr. 1991- Apr. 1992- Mar. 1992 Mar. 1993 Metropolitan area of residence (2) No. Rate No. Rate Pittsburgh, Pa. 120 5.0 164 6.8 Portland, Oreg. 237 15.1 566 34.8 Providence, R.I. 94 10.3 154 16.8 Raleigh-Durham, N.C. 140 15.9 144 15.8 Richmond, Va. 136 15.4 281 31.3 Riverside-San Bernardino, Calif. 385 14.1 794 27.8 Rochester, N.Y. 92 8.6 95 8.8 Sacramento, Calif. 261 18.8 335 23.3 Saint Louis, Mo. 371 14.8 791 31.4 Salt Lake City, Utah 125 11.3 240 21.2 San Antonio, Tex. 217 16.1 308 22.5 San Diego, Calif. 573 22.5 1,167 44.9 San Francisco, Calif. 1,994 122.9 3,430 209.0 San Jose, Calif. 172 11.4 284 18.8 San Juan, P.R. 842 45.4 1,669 89.0 Sarasota, Fla. 124 24.7 117 22.8 Scranton, Pa. 23 3.6 48 7.5 Seattle, Wash. 429 20.6 433 20.4 Springfield, Mass. 98 16.3 177 29.5 Stockton, Calif. 49 9.9 46 9.1 Syracuse, N.Y. 57 7.6 66 8.7 Tacoma, Wash. 38 6.3 38 6.1 Tampa-Saint Petersburg, Fla. 517 24.6 995 46.6 Toledo, Ohio 29 4.7 72 11.7 Tucson, Ariz. 56 8.3 181 26.4 Tulsa, Okla. 89 12.3 185 25.1 Ventura, Calif. 62 9.2 101 14.7 Washington, D.C. 1,352 31.5 1,771 40.6 West Palm Beach, Fla. 408 46.0 733 80.6 Wichita, Kansas 60 12.2 86 17.2 Wilmington, Del. 64 12.3 193 36.3 Youngstown, Ohio 17 2.8 22 3.6 Metropolitan areas with 500,000 or more population 39,005 24.8 59,552 37.4 Metropolitan areas with 50,000 to 500,000 population 4,851 10.4 7,532 15.9 Non-metropolitan areas 2,558 4.9 3,915 7.4 Total 46,622 18.2 71,196 27.4 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 Based on Metropolitan Statistical Areas (MSA) revised December 1992. See technical notes. 3 The current MSA designation for New York City includes includes seven formerly independent MSAs (listed in italics). Because of the epidemiologic significance of these areas, case counts and rates will continue to be listed in this table. See technical notes. Table 2. AIDS cases by metropolitan area, reported in March 1993; cases and rates per 100,000 population by metropolitan area with 500,000 or more population, reported April 1991 through March 1992, and April 1992 through March 1993 (1); and cumulative totals, by area and age group, through March 1993 - continued Cumulative Totals --------------------------------------- Metropolitan Adults/ Children area of residence adolescents < 13 years old Total Pittsburgh, Pa. 902 4 906 Portland, Oreg. 1,716 6 1,722 Providence, R.I. 610 8 618 Raleigh-Durham, N.C. 684 17 701 Richmond, Va. 832 12 844 Riverside-San Bernardino, Calif. 2,268 25 2,293 Rochester, N.Y. 557 8 565 Sacramento, Calif. 1,229 14 1,243 Saint Louis, Mo. 2,053 21 2,074 Salt Lake City, Utah 668 12 680 San Antonio, Tex. 1,350 14 1,364 San Diego, Calif. 4,232 30 4,262 San Francisco, Calif. 15,303 26 15,329 San Jose, Calif. 1,199 10 1,209 San Juan, P.R. 5,876 147 6,023 Sarasota, Fla. 485 10 495 Scranton, Pa. 167 3 170 Seattle, Wash. 2,673 10 2,683 Springfield, Mass. 501 15 516 Stockton, Calif. 231 8 239 Syracuse, N.Y. 352 6 358 Tacoma, Wash. 237 8 245 Tampa-Saint Petersburg, Fla. 3,104 50 3,154 Toledo, Ohio 230 3 233 Tucson, Ariz. 492 3 495 Tulsa, Okla. 476 5 481 Ventura, Calif. 323 1 324 Washington, D.C. 7,936 115 8,051 West Palm Beach, Fla. 2,568 98 2,666 Wichita, Kansas 252 2 254 Wilmington, Del. 500 6 506 Youngstown, Ohio 130 - 130 Metropolitan areas with 500,000 or more population 242,761 3,767 246,528 Metropolitan areas with 50,000 to 500,000 population 27,033 447 27,480 Non-metropolitan areas 14,079 246 14,325 Total (4) 284,840 4,480 289,320 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 Based on Metropolitan Statistical Areas (MSA) revised December 1992. See technical notes. 3 The current MSA designation for New York City includes includes seven formerly independent MSAs (listed in italics). Because of the epidemiologic significance of these areas, case counts and rates will continue to be listed in this table. See technical notes. 4 Totals include 987 persons whose area of residence is unknown. ========================================================================= Table 3. AIDS cases by age group, exposure category, and sex, reported Apr. 1991 through Mar. 1992, Apr. 1992 through Mar. 1993 (1); and cumulative totals, by age group and exposure category, through March 1993, United States Males ------------------------ Apr. 1991- Apr. 1992- Mar. 1992 Mar. 1993 Adult/adolescent exposure category No. (%) No. (%) Men who have sex with men 24,997 (62) 35,106 (58) Injecting drug use 8,393 (21) 12,879 (21) Men who have sex with men and inject drugs 2,608 ( 7) 3,864 ( 6) Hemophilia/coagulation disorder 333 ( 1) 696 ( 1) Heterosexual contact: 1,407 ( 4) 2,400 ( 4) Sex with injecting drug user 611 911 Sex with bisexual male - - Sex with person with hemophilia 5 4 Born in Pattern-II (3) country 318 409 Sex with person born in Pattern-II country 20 28 Sex with transfusion recipient with HIV infection 29 35 Sex with HIV-infected person, risk not specified 424 1,013 Receipt of blood transfusion, blood components, or tissue (4) 428 ( 1) 550 ( 1) Other/risk not identified (5) 1,898 ( 5) 5,071 ( 8) Adult/adolescent subtotal 40,064 (100) 60,566 (100) Pediatric (< 13 years old) exposure category Hemophilia/coagulation disorder 26 ( 6) 16 ( 4) Mother with/at risk for HIV infection: 352 (87) 322 (88) Injecting drug use 144 107 Sex with injecting drug user 60 52 Sex with bisexual male 9 3 Sex with person with hemophilia 5 1 Born in Pattern-II country 22 21 Sex with person born in Pattern-II country 1 3 Sex with transfusion recipient with HIV infection 1 1 Sex with HIV-infected person, risk not specified 34 25 Receipt of blood transfusion, blood components, or tissue 11 16 Has HIV infection, risk not specified 65 93 Receipt of blood transfusion, blood components, or tissue 22 ( 5) 13 ( 4) Risk not identified 3 ( 1) 13 ( 4) Pediatric subtotal 403 (100) 364 (100) Total 40,467 60,930 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 3 See technical notes. 4 Twenty adults/adol. and 2 children developed AIDS after receiving blood screened negative for HIV antibody. Five additional adults developed AIDS after receiving tissue or organs from HIV-infected donors. Two of the 5 received tissues or organs from a donor who was negative for HIV antibody at the time of donation. See N Engl J Med 1992;326:726-32. 5 "Other" refers to 8 health-care workers who developed AIDS after occupational exposure with blood from an HIV-infected person, as documented by evidence of seroconversion; to 2 patients who dev- loped AIDS after exposure to HIV within the health-care setting, as documented by laboratory studies; to 1 person who acquired HIV perinatally and was diagnosed with AIDS after age 13; and to 1 person with intentional self-inoculation of blood from an HIV- infected person. "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. Table 3. AIDS cases by age group, exposure category, and sex, reported Apr. 1991 through Mar. 1992, Apr. 1992 through Mar. 1993 (1); and cumulative totals, by age group and exposure category, through March 1993, United States - continued Females ----------------------- Apr. 1991- Apr. 1992- Mar. 1992 Mar. 1993 Adult/adolescent exposure category No. (%) No. (%) Men who have sex with men - - Injecting drug use 2,797 (48) 4,359 (44) Men who have sex with men and inject drugs - - Hemophilia/coagulation disorder 9 ( 0) 18 ( 0) Heterosexual contact: 2,264 (39) 3,672 (37) Sex with injecting drug user 1,335 1,793 Sex with bisexual male 156 265 Sex with person with hemophilia 19 39 Born in Pattern-II (3) country 176 222 Sex with person born in Pattern-II country 23 19 Sex with transfusion recipient with HIV infection 54 68 Sex with HIV-infected person, risk not specified 501 1,266 Receipt of blood transfusion, blood components, or tissue (4) 263 ( 5) 359 ( 4) Other/risk not identified (5) 488 ( 8) 1,450 (15) Adult/adolescent subtotal 5,821 (100) 9,858 (100) Pediatric (< 13 years old) Exposure category Hemophilia/coagulation disorder - 2 ( 0) Mother with/at risk for HIV infection: 307 (92) 385 (94) Injecting drug use 133 134 Sex with injecting drug user 56 61 Sex with bisexual male 5 8 Sex with person with hemophilia - 3 Born in Pattern-II country 15 15 Sex with person born in Pattern-II country 1 3 Sex with transfusion recipient with HIV infection 2 2 Sex with HIV-infected person, risk not specified 17 52 Receipt of blood transfusion, blood components, or tissue 6 10 Has HIV infection, risk not specified 72 97 Receipt of blood transfusion, blood components, or tissue 15 ( 4) 7 ( 2) Risk not identified 12 ( 4) 14 ( 3) Pediatric subtotal 334 (100) 408 (100) Total 6,155 10,266 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 3 See technical notes. 4 Twenty adults/adol. and 2 children developed AIDS after receiving blood screened negative for HIV antibody. Five additional adults developed AIDS after receiving tissue or organs from infected donors. Two of the 5 received tissues/organs from a donor who was negative for HIV antibody at donation. See N Engl J Med 1992;326:726-32. 5 "Other" refers to 8 health-care workers who developed AIDS after occupational exposure with blood from an HIV-infected person, as documented by evidence of seroconversion; to 2 patients who developed AIDS after exposure with HIV within the health-care setting, as documented by laboratory studies; to 1 person who acquired HIV infection perinatally and was diagnosed with AIDS after age 13; and to 1 person with intentional self-inoculation of blood from an HIV- infected person. "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. Table 3. AIDS cases by age group, exposure category, and sex, reported Apr. 1991 through Mar. 1992, Apr. 1992 through Mar. 1993 (1); and cumulative totals, by age group and exposure category, through March 1993, United States - continued Totals ------------------------------------ Apr. 1991- Apr. 1992- Cumulative Mar. 1992 Mar. 1993 total(2) Adult/adolescent exposure category No. (%) No. (%) No. (%) Men who have sex with men 24,997 (54) 35,106 (50) 160,345 (56) Injecting drug use 11,190 (24) 17,238 (24) 65,778 (23) Men who have sex with men and inject drugs 2,608 ( 6) 3,864 ( 5) 18,041 ( 6) Hemophilia/coagulation disorder 342 ( 1) 714 ( 1) 2,519 ( 1) Heterosexual contact: 3,671 ( 8) 6,072 ( 9) 19,178 ( 7) Sex with injecting drug user 1,946 2,704 9,676 Sex with bisexual male 156 265 980 Sex with person with hemophilia 24 43 154 Born in Pattern-II (3) country 494 631 3,251 Sex with person born in Pattern-II country 43 47 234 Sex with transfusion recipient with HIV infection 83 103 370 Sex with HIV-infected person, risk not specified 925 2,279 4,513 Receipt of blood transfusion, blood components, or tissue (4) 691 ( 2) 909 ( 1) 5,384 ( 2) Other/risk not identified (5) 2,386 ( 5) 6,521 ( 9) 13,595 ( 5) Adult/adolescent subtotal 45,885 (100) 70,424 (100) 284,840 (100) Pediatric (< 13 years old) Exposure category Hemophilia/coagulation disorder 26 ( 4) 18 ( 2) 194 ( 4) Mother with/at risk for HIV infection: 659 (89) 707 (92) 3,887 (87) Injecting drug use 277 241 1,768 Sex with injecting drug user 116 113 761 Sex with bisexual male 14 11 83 Sex with person with hemophilia 5 4 20 Born in Pattern-II country 37 36 293 Sex with person born in Pattern-II country 2 6 20 Sex with transfusion recipient with HIV infection 3 3 18 Sex with HIV-infected person, risk not specified 51 77 234 Receipt of blood transfusion, blood components, or tissue 17 26 90 Has HIV infection, risk not specified 137 190 600 Receipt of blood transfusion, blood components, or tissue 37 ( 5) 20 ( 3) 315 ( 7) Risk not identified 15 ( 2) 27 ( 3) 84 ( 2) Pediatric subtotal 737 (100) 772 (100) 4,480 (100) Total 46,622 71,196 289,320 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 Includes 6 persons known to be infected with human immunodeficiency virus type 2 (HIV-2). See JAMA 1992;267:2775-9. 3 See technical notes. 4 Twenty adults/adol. and 2 children developed AIDS after receiving blood screened negative for HIV antibody. Five additional adults developed AIDS after receiving tissue/organs from HIV-infected donors. Two of the 5 received tissues or organs from a donor who was negative for HIV antibody at the time of donation. See N Engl J Med 1992;326:726-32. 5 "Other" refers to 8 health-care workers who developed AIDS after occupational exposure with blood from an HIV-infected person, as documented by evidence of seroconversion; to 2 patients who developed AIDS after exposure with HIV within the health-care setting, as documented by laboratory studies; to 1 person who acquired HIV infection perinatally and was diagnosed with AIDS after age 13; and to 1 person with intentional self-inoculation of blood from an HIV- infected person. "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. ========================================================================= Table 4. Male adult/adolescent AIDS cases by exposure category and race/ethnicity, reported April 1992 through March 1993 (1); and cumulative totals, through March 1993, United States White, not Hispanic Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Men who have sex with men 23,211 (74) 110,868 (79) Injecting drug use 2,855 ( 9) 10,319 ( 7) Men who have sex with men and inject drugs 2,204 ( 7) 10,339 ( 7) Hemophilia/coagulation disorder 560 ( 2) 2,018 ( 1) Heterosexual contact: 411 ( 1) 1,326 ( 1) Sex with injecting drug user 155 686 Sex with person with hemophilia 1 8 Born in Pattern-II (2) country - 7 Sex with person born in Pattern-II country 7 49 Sex with transfusion recipient with HIV infection 11 58 Sex with HIV-infected person, risk not specified 237 518 Receipt of blood transfusion, blood components, or tissue 356 ( 1) 2,331 ( 2) Risk not identified (3) 1,750 ( 6) 3,881 ( 3) Total 31,347 (100) 141,082 (100) Black, not Hispanic Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Men who have sex with men 7,084 (38) 29,108 (42) Injecting drug use 6,319 (34) 24,231 (35) Men who have sex with men and inject drugs 1,083 ( 6) 4,986 ( 7) Hemophilia/coagulation disorder 79 ( 0) 207 ( 0) Heterosexual contact: 1,529 ( 8) 5,125 ( 7) Sex with injecting drug user 583 1,772 Sex with person with hemophilia 1 3 Born in Pattern-II country 406 2,247 Sex with person born in Pattern-II country 18 67 Sex with transfusion recipient with HIV infection 14 35 Sex with HIV-infected person, risk not specified 507 1,001 Receipt of blood transfusion, blood components, or tissue 113 ( 1) 535 ( 1) Risk not identified 2,212 (12) 4,314 ( 6) Total 18,419 (100) 68,506 (100) 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 See technical notes. 3 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. Table 4. Male adult/adolescent AIDS cases by exposure category and race/ethnicity, reported April 1992 through March 1993 (1); and cumulative totals, through March 1993, United States -- continued Hispanic Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Men who have sex with men 4,341 (43) 18,438 (46) Injecting drug use 3,638 (36) 15,200 (38) Men who have sex with men and inject drugs 534 ( 5) 2,582 ( 6) Hemophilia/coagulation disorder 45 ( 0) 190 ( 0) Heterosexual contact: 447 ( 4) 1,056 ( 3) Sex with injecting drug user 172 511 Sex with person with hemophilia 1 3 Born in Pattern-II (2) country - 11 Sex with person born in Pattern-II country 3 11 Sex with transfusion recipient with HIV infection 8 29 Sex with HIV-infected person, risk not specified 263 491 Receipt of blood transfusion, blood components, or tissue 72 ( 1) 341 ( 1) Risk not identified (3) 1,011 (10) 2,329 ( 6) Total 10,088 (100) 40,136 (100) Asian/Pacific Islander Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Men who have sex with men 264 (71) 1,292 (79) Injecting drug use 15 ( 4) 58 ( 4) Men who have sex with men and inject drugs 11 ( 3) 41 ( 3) Hemophilia/coagulation disorder 9 ( 2) 28 ( 2) Heterosexual contact: 9 ( 2) 20 ( 1) Sex with injecting drug user 1 7 Sex with person with hemophilia - - Born in Pattern-II country 1 3 Sex with person born in Pattern-II country - 1 Sex with transfusion recipient with HIV infection 2 2 Sex with HIV-infected person, risk not specified 5 7 Receipt of blood transfusion, blood components, or tissue 8 ( 2) 64 ( 4) Risk not identified 58 (16) 126 ( 8) Total 374 (100) 1,629 (100) 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 See technical notes. 3 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. Table 4. Male adult/adolescent AIDS cases by exposure category and race/ethnicity, reported April 1992 through March 1993 (1); and cumulative totals, through March 1993, United States -- continued American Indian/ Alaska Native Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Men who have sex with men 113 (67) 310 (65) Injecting drug use 14 ( 8) 51 (11) Men who have sex with men and inject drugs 27 (16) 77 (16) Hemophilia/coagulation disorder 3 ( 2) 11 ( 2) Heterosexual contact: 1 ( 1) 5 ( 1) Sex with injecting drug user - 4 Sex with person with hemophilia - - Born in Pattern-II (2) country - - Sex with person born in Pattern-II country - - Sex with transfusion recipient with HIV infection - - Sex with HIV-infected person, risk not specified 1 1 Receipt of blood transfusion, blood components, or tissue 1 ( 1) 3 ( 1) Risk not identified (3) 10 ( 6) 19 ( 4) Total 169 (100) 476 (100) Cumulative totals (4) Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Men who have sex with men 35,106 (58) 160,345 (64) Injecting drug use 12,879 (21) 49,962 (20) Men who have sex with men and inject drugs 3,864 ( 6) 18,041 ( 7) Hemophilia/coagulation disorder 696 ( 1) 2,460 ( 1) Heterosexual contact: 2,400 ( 4) 7,540 ( 3) Sex with injecting drug user 911 2,980 Sex with person with hemophilia 4 15 Born in Pattern-II country 409 2,274 Sex with person born in Pattern-II country 28 128 Sex with transfusion recipient with HIV infection 35 125 Sex with HIV-infected person, risk not specified 1,013 2,018 Receipt of blood transfusion, blood components, or tissue 550 ( 1) 3,280 ( 1) Risk not identified 5,071 ( 8) 10,735 ( 4) Total 60,566 (100) 252,363 (100) 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 See technical notes. 3 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. 4 Includes 534 men whose race/ethnicity is unknown. ========================================================================= Table 5. Female adult/adolescent AIDS cases by exposure category and race/ethnicity, reported April 1992 through March 1993 (1); and cumulative totals, through March 1993, United States White, not Hispanic Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Injecting drug use 1,047 (43) 3,481 (42) Hemophilia/coagulation disorder 9 ( 0) 39 ( 0) Heterosexual contact: 859 (35) 2,748 (33) Sex with injecting drug user 378 1,342 Sex with bisexual male 121 495 Sex with person with hemophilia 28 112 Born in Pattern-II (2) country - 2 Sex with person born in Pattern-II country 1 12 Sex with transfusion recipient with HIV infection 44 155 Sex with HIV-infected person, risk not specified 287 630 Receipt of blood transfusion, blood components, or tissue 177 ( 7) 1,282 (16) Risk not identified (3) 331 (14) 708 ( 9) Total 2,423 (100) 8,258 (100) Black, not Hispanic Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Injecting drug use 2,459 (46) 9,097 (53) Hemophilia/coagulation disorder 6 ( 0) 14 ( 0) Heterosexual contact: 1,959 (37) 6,147 (36) Sex with injecting drug user 892 3,366 Sex with bisexual male 94 337 Sex with person with hemophilia 8 18 Born in Pattern-II country 218 965 Sex with person born in Pattern-II country 18 91 Sex with transfusion recipient with HIV infection 14 45 Sex with HIV-infected person, risk not specified 715 1,325 Receipt of blood transfusion, blood components, or tissue 104 ( 2) 465 ( 3) Risk not identified 821 (15) 1,562 ( 9) Total 5,349 (100) 17,285 (100) 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 See technical notes. 3 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. Table 5. Female adult/adolescent AIDS cases by exposure category and race/ethnicity, reported April 1992 through March 1993 (1); and cumulative totals, through March 1993, United States -- continued Hispanic Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Injecting drug use 818 (41) 3,136 (47) Hemophilia/coagulation disorder 2 ( 0) 5 ( 0) Heterosexual contact: 813 (41) 2,634 (40) Sex with injecting drug user 509 1,938 Sex with bisexual male 39 121 Sex with person with hemophilia 3 7 Born in Pattern-II (2) country 3 8 Sex with person born in Pattern-II country - 3 Sex with transfusion recipient with HIV infection 8 40 Sex with HIV-infected person, risk not specified 251 517 Receipt of blood transfusion, blood components, or tissue 65 ( 3) 297 ( 4) Risk not identified (3) 277 (14) 545 ( 8) Total 1,975 (100) 6,617 (100) Asian/Pacific Islander Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Injecting drug use 8 (13) 26 (15) Hemophilia/coagulation disorder 1 ( 2) 1 ( 1) Heterosexual contact: 31 (49) 68 (39) Sex with injecting drug user 8 21 Sex with bisexual male 9 21 Sex with person with hemophilia - 2 Born in Pattern-II country 1 1 Sex with person born in Pattern-II country - - Sex with transfusion recipient with HIV infection 2 4 Sex with HIV-infected person, risk not specified 11 19 Receipt of blood transfusion, blood components, or tissue 10 (16) 49 (28) Risk not identified 13 (21) 31 (18) Total 63 (100) 175 (100) 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 See technical notes. 3 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. Table 5. Female adult/adolescent AIDS cases by exposure category and race/ethnicity, reported April 1992 through March 1993 (1); and cumulative totals, through March 1993, United States -- continued American Indian/ Alaska Native Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Injecting drug use 14 (50) 43 (55) Hemophilia/coagulation disorder - - Heterosexual contact: 8 (29) 20 (26) Sex with injecting drug user 6 15 Sex with bisexual male 1 3 Sex with person with hemophilia - - Born in Pattern-II (2) country - - Sex with person born in Pattern-II country - - Sex with transfusion recipient with HIV infection - - Sex with HIV-infected person, risk not specified 1 2 Receipt of blood transfusion, blood components, or tissue 3 (11) 8 (10) Risk not identified (3) 3 (11) 7 ( 9) Total 28 (100) 78 (100) Cumulative totals (4) Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Injecting drug use 4,359 (44) 15,816 (49) Hemophilia/coagulation disorder 18 ( 0) 59 ( 0) Heterosexual contact: 3,672 (37) 11,638 (36) Sex with injecting drug user 1,793 6,696 Sex with bisexual male 265 980 Sex with person with hemophilia 39 139 Born in Pattern-II country 222 977 Sex with person born in Pattern-II country 19 106 Sex with transfusion recipient with HIV infection 68 245 Sex with HIV-infected person, risk not specified 1,266 2,495 Receipt of blood transfusion, blood components, or tissue 359 ( 4) 2,104 ( 6) Risk not identified 1,450 (15) 2,860 ( 9) Total 9,858 (100) 32,477 (100) 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 See technical notes. 3 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. 4 Includes 64 women whose race/ethnicity is unknown. ========================================================================= Table 6. Pediatric AIDS cases by exposure category and race/ethnicity reported April 1992 through March 1993; and cumulative totals, through March 1993, United States White, not Hispanic Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Hemophilia/coagulation disorder 9 ( 7) 131 (14) Mother with/at risk for HIV infection: 100 (83) 598 (66) Injecting drug use 32 269 Sex with injecting drug user 13 111 Sex with bisexual male 10 37 Sex with person with hemophilia 2 12 Born in Pattern-II (1) country - 3 Sex with person born in Pattern-II country - - Sex with transfusion recipient with HIV infection 1 6 Sex with HIV-infected person, risk not specified 9 41 Receipt of blood transfusion, blood components, or tissue 5 26 Has HIV infection, risk not specified 28 93 Receipt of blood transfusion, blood components, or tissue 6 ( 5) 162 (18) Risk not identified (2) 6 ( 5) 16 ( 2) Total 121 (100) 907 (100) Black, not Hispanic Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Hemophilia/coagulation disorder 3 ( 1) 26 ( 1) Mother with/at risk for HIV infection: 442 (95) 2,300 (94) Injecting drug use 148 1,044 Sex with injecting drug user 58 348 Sex with bisexual male 1 28 Sex with person with hemophilia 1 5 Born in Pattern-II country 36 288 Sex with person born in Pattern-II country 6 18 Sex with transfusion recipient with HIV infection - 4 Sex with HIV-infected person, risk not specified 50 127 Receipt of blood transfusion, blood components, or tissue 11 40 Has HIV infection, risk not specified 131 398 Receipt of blood transfusion, blood components, or tissue 5 ( 1) 70 ( 3) Risk not identified 17 ( 4) 51 ( 2) Total 467 (100) 2,447 (100) 1 See technical notes. 2 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure remains unidentified after investigation. Table 6. Pediatric AIDS cases by exposure category and race/ethnicity reported April 1992 through March 1993; and cumulative totals, through March 1993, United States - continued Hispanic Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Hemophilia/coagulation disorder 5 ( 3) 33 ( 3) Mother with/at risk for HIV infection 155 (90) 957 (88) Injecting drug use 55 443 Sex with injecting drug user 40 295 Sex with bisexual male - 17 Sex with person with hemophilia 1 3 Born in Pattern-II (1) country - 2 Sex with person born in Pattern-II country - 1 Sex with transfusion recipient with HIV infection 2 8 Sex with HIV-infected person, risk not specified 18 62 Receipt of blood transfusion, blood components, or tissue 10 24 Has HIV infection, risk not specified 29 102 Receipt of blood transfusion, blood components, or tissue 8 ( 5) 75 ( 7) Risk not identified (2) 4 ( 2) 17 ( 2) Total 172 (100) 1,082 (100) Asian/Pacific Islander Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Hemophilia/coagulation disorder - 3 (16) Mother with/at risk for HIV infection 1 (100) 9 (47) Injecting drug use 1 3 Sex with injecting drug user - 2 Sex with bisexual male - 1 Sex with person with hemophilia - - Born in Pattern-II country - - Sex with person born in Pattern-II country - - Sex with transfusion recipient with HIV infection - - Sex with HIV-infected person, risk not specified - 1 Receipt of blood transfusion, blood components, or tissue - - Has HIV infection, risk not specified - 2 Receipt of blood transfusion, blood components, or tissue - 7 (37) Risk not identified - - Total 1 (100) 19 (100) 1 See technical notes. 2 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure remains unidentified after investigation. Table 6. Pediatric AIDS cases by exposure category and race/ethnicity reported April 1992 through March 1993; and cumulative totals, through March 1993, United States - continued American Indian/ Alaska Native Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Hemophilia/coagulation disorder 1 (20) 1 ( 7) Mother with/at risk for HIV infection 4 (80) 14 (93) Injecting drug use 1 5 Sex with injecting drug user 2 3 Sex with bisexual male - - Sex with person with hemophilia - - Born in Pattern-II (1) country - - Sex with person born in Pattern-II country - - Sex with transfusion recipient with HIV infection - - Sex with HIV-infected person, risk not specified - 2 Receipt of blood transfusion, blood components, or tissue - - Has HIV infection, risk not specified 1 4 Receipt of blood transfusion, blood components, or tissue - - Risk not identified (2) - - Total 5 (100) 15 (100) Cumulative totals (3) Apr. 1992- Cumulative Mar. 1993 total Exposure category No. (%) No. (%) Hemophilia/coagulation disorder 18 ( 2) 194 ( 4) Mother with/at risk for HIV infection 707 (92) 3,887 (87) Injecting drug use 241 1,768 Sex with injecting drug user 113 761 Sex with bisexual male 11 83 Sex with person with hemophilia 4 20 Born in Pattern-II country 36 293 Sex with person born in Pattern-II country 6 20 Sex with transfusion recipient with HIV infection 3 18 Sex with HIV-infected person, risk not specified 77 234 Receipt of blood transfusion, blood components, or tissue 26 90 Has HIV infection, risk not specified 190 600 Receipt of blood transfusion, blood components, or tissue 20 ( 3) 315 ( 7) Risk not identified 27 ( 3) 84 ( 2) Total 772 (100) 4,480 (100) 1 See technical notes. 2 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure remains unidentified after investigation. 3 Includes 10 children whose race/ethnicity is unknown. ========================================================================= Table 7. AIDS cases in adolescents and adults under age 25, by sex and exposure category, reported April 1991 through March 1992, April 1992 through March 1993 (1); and cumulative totals through March 1993, United States 13-19 years old Apr. 1991- Apr. 1992- Cumulative Mar. 1992 Mar. 1993 total Male exposure category No. (%) No. (%) No. (%) Men who have sex with men 30 (29) 67 (29) 273 (33) Injecting drug use 5 ( 5) 11 ( 5) 55 ( 7) Men who have sex with men and inject drugs 4 ( 4) 6 ( 3) 40 ( 5) Hemophilia/coagulation disorder 48 (47) 112 (48) 359 (43) Heterosexual contact: 2 ( 2) 12 ( 5) 25 ( 3) Sex with injecting drug user - 5 9 Sex with person with hemophilia - 1 1 Born in Pattern-II (2) country - 1 8 Sex with person born in Pattern-II country 1 - 1 Sex with transfusion recipient with HIV infection - - - Sex with HIV-infected person, risk not specified 1 5 6 Receipt of blood transfusion, blood components, or tissue 5 ( 5) 5 ( 2) 32 ( 4) Risk not identified (3) 8 ( 8) 19 ( 8) 44 ( 5) Male subtotal 102 (100) 232 (100) 828 (100) 13-19 years old Apr. 1991- Apr. 1992- Cumulative Mar. 1992 Mar. 1993 total Female exposure category No. (%) No. (%) No. (%) Injecting drug use 13 (27) 13 (11) 77 (23) Hemophilia/coagulation disorder 1 ( 2) - 4 ( 1) Heterosexual contact: 24 (50) 68 (59) 170 (50) Sex with injecting drug user 15 29 101 Sex with bisexual male 1 4 8 Sex with person with hemophilia 2 2 6 Born in Pattern-II country 1 3 9 Sex with person born in Pattern-II country 1 1 2 Sex with transfusion recipient with HIV infection - - 1 Sex with HIV-infected person, risk not specified 4 29 43 Receipt of blood transfusion, blood components, or tissue 1 ( 2) 5 ( 4) 30 ( 9) Risk not identified 9 (19) 30 (26) 58 (17) Female subtotal 48 (100) 116 (100) 339 (100) Total 150 348 1,167 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 See technical notes. 3 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. Table 7. AIDS cases in adolescents and adults under age 25, by sex and exposure category, reported April 1991 through March 1992, April 1992 through March 1993 (1); and cumulative totals through March 1993, United States - continued 20-24 years old Apr. 1991- Apr. 1992- Cumulative Mar. 1992 Mar. 1993 total Male exposure category No. (%) No. (%) No. (%) Men who have sex with men 687 (60) 1,092 (61) 5,745 (65) Injecting drug use 171 (15) 191 (11) 1,077 (12) Men who have sex with men and inject drugs 120 (10) 138 ( 8) 920 (10) Hemophilia/coagulation disorder 43 ( 4) 103 ( 6) 321 ( 4) Heterosexual contact: 51 ( 4) 83 ( 5) 304 ( 3) Sex with injecting drug user 25 28 115 Sex with person with hemophilia - - 1 Born in Pattern-II (2) country 7 12 89 Sex with person born in Pattern-II country - 1 1 Sex with transfusion recipient with HIV infection 2 1 6 Sex with HIV-infected person, risk not specified 17 41 92 Receipt of blood transfusion, blood components, or tissue 10 ( 1) 11 ( 1) 75 ( 1) Risk not identified (3) 61 ( 5) 168 ( 9) 382 ( 4) Male subtotal 1,143 (100) 1,786 (100) 8,824 (100) 20-24 years old Apr. 1991- Apr. 1992- Cumulative Mar. 1992 Mar. 1993 total Female exposure category No. (%) No. (%) No. (%) Injecting drug use 115 (33) 184 (29) 765 (36) Hemophilia/coagulation disorder - 4 ( 1) 8 ( 0) Heterosexual contact: 186 (53) 310 (48) 1,037 (49) Sex with injecting drug user 112 160 612 Sex with bisexual male 15 15 86 Sex with person with hemophilia 1 5 22 Born in Pattern-II country 8 6 58 Sex with person born in Pattern-II country 1 - 10 Sex with transfusion recipient with HIV infection - - 5 Sex with HIV-infected person, risk not specified 49 124 244 Receipt of blood transfusion, blood components, or tissue 11 ( 3) 15 ( 2) 71 ( 3) Risk not identified 38 (11) 129 (20) 244 (11) Female subtotal 350 (100) 642 (100) 2,125 (100) Total 1,493 2,428 10,949 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 See technical notes. 3 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. ========================================================================= Table 8. AIDS cases by sex, age at diagnosis, and race/ethnicity, reported through March 1993 (1), United States White, not Black, not Hispanic Hispanic Hispanic Males Age at diagnosis (years) No. (%) No. (%) No. (%) Under 5 304 ( 0) 1,063 ( 2) 443 ( 1) 5-12 228 ( 0) 168 ( 0) 132 ( 0) 13-19 393 ( 0) 261 ( 0) 157 ( 0) 20-24 4,222 ( 3) 2,817 ( 4) 1,693 ( 4) 25-29 20,725 (15) 10,323 (15) 6,618 (16) 30-34 32,997 (23) 16,222 (23) 10,009 (25) 35-39 31,424 (22) 16,219 (23) 9,022 (22) 40-44 22,304 (16) 10,629 (15) 5,917 (15) 45-49 13,155 ( 9) 5,540 ( 8) 3,136 ( 8) 50-54 7,130 ( 5) 3,083 ( 4) 1,723 ( 4) 55-59 4,147 ( 3) 1,754 ( 3) 1,008 ( 2) 60-64 2,487 ( 2) 949 ( 1) 499 ( 1) 65 or older 2,098 ( 1) 709 ( 1) 354 ( 1) Male subtotal 141,614 (100) 69,737 (100) 40,711 (100) White, not Black, not Hispanic Hispanic Hispanic Females Age at diagnosis (years) No. (%) No. (%) No. (%) Under 5 302 ( 3) 1,050 ( 6) 413 ( 6) 5-12 73 ( 1) 166 ( 1) 94 ( 1) 13-19 84 ( 1) 200 ( 1) 52 ( 1) 20-24 542 ( 6) 1,085 ( 6) 477 ( 7) 25-29 1,532 (18) 3,145 (17) 1,396 (20) 30-34 1,925 (22) 4,549 (25) 1,717 (24) 35-39 1,467 (17) 3,993 (22) 1,358 (19) 40-44 853 (10) 2,148 (12) 783 (11) 45-49 448 ( 5) 898 ( 5) 353 ( 5) 50-54 295 ( 3) 554 ( 3) 214 ( 3) 55-59 295 ( 3) 312 ( 2) 124 ( 2) 60-64 228 ( 3) 199 ( 1) 69 ( 1) 65 or older 589 ( 7) 202 ( 1) 74 ( 1) Female subtotal 8,633 (100) 18,501 (100) 7,124 (100) Total 150,247 88,238 47,835 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. Table 8. AIDS cases by sex, age at diagnosis, and race/ethnicity, reported through March 1993 (1), United States - continued Asian/Pacific American Indian/ Islander Alaska Native Total (2) Males Age at diagnosis (years) No. (%) No. (%) No. (%) Under 5 7 ( 0) 8 ( 2) 1,828 ( 1) 5-12 6 ( 0) 1 ( 0) 535 ( 0) 13-19 8 ( 0) 9 ( 2) 828 ( 0) 20-24 57 ( 3) 21 ( 4) 8,824 ( 3) 25-29 222 (14) 92 (19) 38,057 (15) 30-34 334 (20) 132 (27) 59,804 (23) 35-39 359 (22) 98 (20) 57,256 (22) 40-44 279 (17) 61 (13) 39,282 (15) 45-49 180 (11) 31 ( 6) 22,090 ( 9) 50-54 88 ( 5) 13 ( 3) 12,065 ( 5) 55-59 51 ( 3) 10 ( 2) 6,992 ( 3) 60-64 16 ( 1) 7 ( 1) 3,963 ( 2) 65 or older 35 ( 2) 2 ( 0) 3,202 ( 1) Male subtotal 1,642 (100) 485 (100) 254,726 (100) Asian/Pacific American Indian/ Islander Alaska Native Total (2) Females Age at diagnosis (years) No. (%) No. (%) No. (%) Under 5 - 6 ( 7) 1,777 ( 5) 5-12 6 ( 3) - 340 ( 1) 13-19 1 ( 1) 1 ( 1) 339 ( 1) 20-24 7 ( 4) 7 ( 8) 2,125 ( 6) 25-29 18 (10) 15 (18) 6,114 (18) 30-34 34 (19) 24 (29) 8,264 (24) 35-39 28 (15) 11 (13) 6,873 (20) 40-44 34 (19) 10 (12) 3,835 (11) 45-49 16 ( 9) 5 ( 6) 1,726 ( 5) 50-54 9 ( 5) 1 ( 1) 1,074 ( 3) 55-59 7 ( 4) 1 ( 1) 741 ( 2) 60-64 10 ( 6) 2 ( 2) 508 ( 1) 65 or older 11 ( 6) 1 ( 1) 878 ( 3) Female subtotal 181 (100) 84 (100) 34,594 (100) Total 1,823 569 289,320 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 Includes 537 males and 71 females whose race/ethnicity is unknown. ========================================================================= Table 9. Adult/adol. AIDS cases, case-fatality rates (1), and deaths, by half-year and age group, through March 1993 (2), United States Adults/adolescents Cases diagnosed Case-fatality Deaths occurring Half-year during interval rate during interval Before 1981 84 84.5 31 1981 Jan. - June 97 89.7 39 July - Dec. 206 90.3 88 1982 Jan. - June 406 92.1 154 July - Dec. 700 91.0 289 1983 Jan. - June 1,289 93.8 524 July - Dec. 1,654 93.2 938 1984 Jan. - June 2,576 92.7 1,407 July - Dec. 3,392 92.9 1,974 1985 Jan. - June 4,922 92.3 2,827 July - Dec. 6,343 91.4 3,891 1986 Jan. - June 8,359 90.2 5,102 July - Dec. 9,968 88.2 6,560 1987 Jan. - June 12,990 88.5 7,599 July - Dec. 14,397 85.3 7,985 1988 Jan. - June 16,604 82.8 9,370 July - Dec. 17,124 82.0 10,709 1989 Jan. - June 19,585 77.5 12,492 July - Dec. 19,707 75.0 14,383 1990 Jan. - June 21,392 68.2 14,072 July - Dec. 20,846 62.4 14,940 1991 Jan. - June 23,690 53.3 15,497 July - Dec. 24,610 42.5 16,818 1992 Jan. - June 26,228 28.9 16,345 July - Dec. 22,768 15.4 13,125 1993 Jan. - Mar. (2) 4,903 6.2 2,509 Total (3) 284,840 63.2 179,917 1 Case-fatality rates are calculated for each half-year by date of diagnosis. Each 6-month case-fatality rate is the number of deaths ever reported among cases diagnosed in that period (re- gardless of the year of death), divided by the number of total cases diagnosed in that period, multiplied by 100. For example, during the interval January through June 1982, AIDS was diagnosed in 406 adults/adolescents. Through March 1993, 374 of these were reported as dead. Therefore, the case-fatality rate is 92.1 (374 divided by 406, multiplied by 100). The case-fatality rates shown here may be underestimates because of incomplete reporting of deaths. Reported deaths are not necessarily caused by HIV-related disease. 2 Includes 3 months of data collected under the 1993 AIDS surveillance case defintions for adults and adolescents. 3 Death totals include 249 adults/adolescents known to have died, but whose dates of death are unknown. Table 9. Pediatric AIDS cases, case-fatality rates (1), and deaths, by half-year and age group, through March 1993 (2), United States -- continued Children < 13 years old Cases diagnosed Case-fatality Deaths occurring Half-year during interval rate during interval Before 1981 7 71.4 1 1981 Jan. - June 11 81.8 2 July - Dec. 5 100.0 7 1982 Jan. - June 13 84.6 8 July - Dec. 15 80.0 5 1983 Jan. - June 33 100.0 13 July - Dec. 42 90.5 16 1984 Jan. - June 52 84.6 26 July - Dec. 59 83.1 22 1985 Jan. - June 98 76.5 44 July - Dec. 129 82.2 70 1986 Jan. - June 135 83.0 64 July - Dec. 188 70.7 92 1987 Jan. - June 222 70.7 118 July - Dec. 257 66.1 168 1988 Jan. - June 256 64.1 134 July - Dec. 339 58.7 173 1989 Jan. - June 339 58.7 170 July - Dec. 335 53.1 185 1990 Jan. - June 349 47.9 192 July - Dec. 371 38.8 190 1991 Jan. - June 338 38.5 158 July - Dec. 287 27.2 185 1992 Jan. - June 342 27.2 160 July - Dec. 228 19.3 133 1993 Jan. - Mar. (2) 30 10.0 18 Total (3) 4,480 52.6 2,358 1 Case-fatality rates are calculated for each half-year by date of diagnosis. Each 6-month case-fatality rate is the number of deaths ever reported among cases diagnosed in that period (re- gardless of the year of death), divided by the number of total cases diagnosed in that period, multiplied by 100. For example, during the interval January through June 1982, AIDS was diagnosed in 13 children. Through March 1993, 11 of these 13 were reported as dead. Therefore, the case-fatality rate is 84.6 (11 divided by 13, multiplied by 100). The case-fatality rates shown here may be underestimates because of incomplete reporting of deaths. Reported deaths are not necessarily caused by HIV-related disease. 2 Includes 3 months of data collected under the 1993 AIDS surveillance case defintions for adults and adolescents. 3 Death totals include 4 children known to have died, but whose dates of death are unknown. ========================================================================= Table 10. AIDS cases by year of diagnosis and definition category, diagnosed through March 1993 (1), United States Period of diagnosis (2) Before Apr. 1989- Apr. 1990- Mar. 1989 Mar. 1990 Mar. 1991 Definition category No. (%) No. (%) No. (%) Pre-1987 definition 91,625 (81) 27,899 (68) 27,561 (63) 1987 definition 20,524 (18) 12,521 (30) 14,334 (33) 1993 definition (3) 528 ( 0) 820 ( 2) 2,042 ( 5) Severe HIV-related immunosuppression (4) 381 671 1,668 Pulmonary tuberculosis 136 137 354 Recurrent pneumonia 9 12 18 Invasive cervical cancer 4 1 3 Total 112,677 (100) 41,240 (100) 43,937 (100) Period of diagnosis Apr. 1991- Apr. 1992- Cumulative Mar. 1992 Mar. 1993 total Definition category No. (%) No. (%) No. (%) Pre-1987 definition 27,953 (55) 17,188 (42) 192,226 (66) 1987 definition 16,552 (33) 11,581 (28) 75,512 (26) 1993 definition 6,210 (12) 11,982 (29) 21,582 ( 7) Severe HIV-related immunosuppression 5,470 11,094 19,284 Pulmonary tuberculosis 686 708 2,021 Recurrent pneumonia 49 157 245 Invasive cervical cancer 8 25 41 Total 50,715 (100) 40,751 (100) 289,320 (100) 1 Includes 3 months of data collected under the 1993 AIDS surveillance case definition for adults and adolescents. 2 Some persons diagnosed with a condition meeting the 1993 definition have diagnosis dates prior to 1993. 3 The sum of diagnoses listed for the four conditions under the 1993 definition may not equal the 1993 definition total because some persons have more than one diagnosis from the added conditions pulmonary tuberculosis, recurrent pneumonia, and invasive cervical cancer. 4 Defined as CD4+ T-lymphocyte count of less than 200 cells/uL or a CD4+ percentage less than 14 in persons with laboratory confirmation of HIV infection. ========================================================================= Table 11. Health-care workers with documented and possible occupationally acquired AIDS/HIV infection, by occupation, reported through March 1993, United States (1) Documented Possible occupational occupational transmission (2) transmission (3) Occupation No. No. Dental worker, including dentist - 6 Embalmer/morgue technician - 3 Emergency medical technician/paramedic - 7 Health aide/attendant 1 7 Housekeeper/maintenace worker 1 5 Laboratory technician, clinical 14 12 Laboratory technician, nonclinical 1 1 Nurse 12 17 Physician, nonsurgical 4 8 Physician, surgical - 2 Respiratory therapist 1 1 Surgical technician 1 1 Technician/therapist, other than those listed above 1 3 Other health-care occupations - 2 Total 36 75 1 Health-care workers are defined as those persons, including students and trainees, who have worked in a health-care, clinical, or HIV laboratory setting at any time since 1978. See MMWR 1992;41:823-5. 2 Health-care workers who had documented HIV seroconversion after occupational exposure: 31 had percutaneous exposure, 4 had muco- cutaneous exposure, 1 had both percutaneous and mucocutaneous ex- posures. Thirty-three exposures were to blood from an HIV-infected person, 1 to visibly bloody fluid, 1 to an unspecified fluid and 1 to a concentrated virus in a laboratory. Eight of these health- care workers have developed AIDS. 3 These health-care workers have been investigated and are without identifiable behavioral or transfusion risks; each reported percutaneous or mucocutaneous occupational exposures with blood or body fluids, or laboratory solutions containing HIV, but HIV seroconversion specifically resulting from an occupational exposure was not documented. ========================================================================= Table 12. Adult/adolescent AIDS cases by single and multiple exposure categories, reported through March 1993, United States AIDS cases Exposure category No. ( %) Single mode of exposure Men who have sex with men 154,623 (54) Injecting drug use 55,818 (20) Hemophilia/coagulation disorder 1,846 ( 1) Heterosexual contact 18,500 ( 6) Receipt of transfusion (1) 5,379 ( 2) Receipt of transplant of tissues/organs (2) 5 ( 0) Other (3) 12 ( 0) Single mode of exposure subtotal 236,188 (83) Multiple modes of exposure Men who have sex with men;injecting drug use 16,205 ( 6) Men who have sex with men;hemophilia/coagulation disorder 69 ( 0) Men who have sex with men;heterosexual contact 3,179 ( 1) Men who have sex with men; receipt of transfusion/transplant 2,302 ( 1) Injecting drug use;hemophilia/coagulation disorder 73 ( 0) Injecting drug use;heterosexual contact 8,501 ( 3) Injecting drug use;receipt of transfusion/transplant 1,003 ( 0) Hemophilia/coagulation disorder;heterosexual contact 16 ( 0) Hemophilia/coagulation disorder; receipt of transfusion/transplant 644 ( 0) Heterosexual contact;receipt of transfusion/transplant 678 ( 0) Men who have sex with men;injecting drug use; hemophilia/coagulation disorder 16 ( 0) Men who have sex with men;injecting drug use; heterosexual contact 1,404 ( 0) Men who have sex with men;injecting drug use; receipt of transfusion/transplant 350 ( 0) Men who have sex with men;hemophilia/coagulation disorder; heterosexual contact 3 ( 0) Men who have sex with men;hemophilia/coagulation disorder; receipt of transfusion/transplant 24 ( 0) Men who have sex with men;heterosexual contact; receipt of transfusion/transplant 144 ( 0) Injecting drug use;hemophilia/coagulation disorder; heterosexual contact 16 ( 0) Injecting drug use;hemophilia/coagulation disorder; receipt of transfusion/transplant 23 ( 0) Injecting drug use;heterosexual contact; receipt of transfusion/transplant 338 ( 0) Hemophilia/coagulation disorder;heterosexual contact; receipt of transfusion/transplant 13 ( 0) Men who have sex with men;injecting drug use; hemophilia/coagulation disorder;heterosexual contact 2 ( 0) Men who have sex with men;injecting drug use; hemophilia/coagulation disorder; receipt of transfusion/transplant 5 ( 0) Men who have sex with men;injecting drug use; heterosexual contact; receipt of transfusion/transplant 59 ( 0) Men who have sex with men;hemophilia/coagulation disorder; heterosexual contact; receipt of transfusion/transplant 1 ( 0) Injecting drug use;hemophilia/coagulation disorder; heterosexual contact; receipt of transfusion/transplant 6 ( 0) Multiple modes of exposure subtotal 35,074 (12) Risk not identified (4) 13,583 ( 5) Total 284,840 (100) 1 Includes twenty adult/adolescents and 2 children who developed AIDS after receiving blood screen negative for HIV antibody. 2 Five adults developed AIDS after receiving tissue from HIV- infected donors. Two of the 5 received tissue or organs from a donor who was negative for HIV antibody at the time of donation. See N Engl J Med 1992;326:726-32. 3 "Other" refers to 8 health-care workers who developed AIDS developed AIDS after occupational exposure with blood from an HIV- infected person, as documented by evidence of seroconversion; to 2 patients who developed AIDS after exposure with HIV within the health-care setting, as documented by laboratory studies; to 1 person who acquired HIV infection perinatally and was diagnosed with AIDS after age 13; and to 1 person with intentional self-inoculation of blood from an HIV-infected person. 4 "Risk not identified" refers to persons whose mode of exposure to HIV is unknown. This includes persons under investigation; persons who died, were lost to follow-up, or declined interview; and persons whose mode of exposure to HIV remains unidentified after investigation. =========================================================================