AIDS Daily Summary November 29, 1993 The Centers for Disease Control and Prevention (CDC) National AIDS Clearinghouse makes available the following information as a public service only. Providing this information does not constitute endorsement by the CDC, the CDC Clearinghouse, or any other organization. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC Clearinghouse should be cited as the source of this information. Copyright 1993, Information, Inc., Bethesda, MD "The Politics of AIDS" Washington Post (11/29/93) P. D1 (Weinraub, Judith) Following her September dismissal from the District of Columbia's Agency for HIV/AIDS, former chief Caitlin Ryan awaits a conference on her appeal, scheduled for next Monday. She was fired following allegations that she improperly steered a $200,000 AIDS education contract away from the Abundant Life Clinic, which is headed by the health minister of the Nation of Islam, Dr. Abdul Alim Muhammad. Ryan is also accused of stating that "Muslims hate gays" in defense of her actions. The former agency chief denies any impropriety. As she prepares her appeal, others reflect on the impact her dismissal has had on the agency. According to sources within and outside of the office, Ryan gave the agency a facelift and developed a highly acclaimed plan to combat AIDS. Some say that Ryan--a white, openly lesbian woman--was set up. Ryan admits to attending a meeting of a review panel for the AIDS contract, but claims to have done so only at the invitation of staffers who said they needed her help. Ryan supporters suggest that she was deliberately invited so that her attendance could be distorted into something that could get her fired. Ryan, however, is determined to clear her name; in the meanwhile, the agency is floundering. "The most unfortunate piece about all of this is that nothing constructive happened," says Alexander Robinson, head of an AIDS consortium. "We have not gotten a dynamite new person. And the contract wasn't even awarded to people she allegedly steered it away from. Nothing has been accomplished." "Romania Is Linked to Tainted Blood" New York Times (11/28/93) P. 15 (Perlez, Jane) German investigators have pinpointed Romanian blood products as one source of HIV-contaminated blood that was distributed by German firm UB Plasma. Romania's health minister has admitted to the sale of the blood from the German company's subsidiary in Bucharest, UB Plasma Roma, which sold 1,500 liters of plasma to the parent company this year. The officials who allowed the sale of the blood insist that it was tainted only with hepatitis B, not with the AIDS virus. But WHO officials have been told that "one or two" of the 1,500 liters from Romania were contaminated with HIV. According to officials, the Romanian health authorities and their blood program will be investigated in January by doctors from the Council of Europe. The Romanians signed a Council of Europe agreement in 1990 that prohibits cross-border trade in untested blood, said the officials. "Lecture on Sexism's Role in AIDS" Chicago Tribune (11/28/93) P. 6-13 Ann Meredith, a 45-year-old documentary photographer from New York, believes that only through discussion about AIDS and women can society recognize how sexual discrimination weakens the ability of women to protect themselves from HIV. So Meredith will do just that at a lecture at the Art Institute of Chicago this Wednesday. Her presentation will include photographs she took in Kenya, slides, and a video of interviews with infected black women. Even women who are not intravenous drug users and have not had multiple sex partners are at risk if they are financially dependent on their husbands or partners, says Meredith. If the man in such a relationship is not truthful about his sexual history and/or refuses to wear a condom, the woman's risk is elevated. "It is very hard to trust even someone you know and love to tell the truth in this area," Meredith warns. "AIDS Spiral Raises Rights Issue in China" Reuters (11/23/93) (Quinn, Andrew) Beijing--In China's recent past, the very few numbers of isolated AIDS cases were listed and filed, and the public believed that the world's most populous country was safe from the deadly disease that is ravaging other nations. Lately, the numbers have been piling up until it has become clear that China, too, is in danger of an AIDS explosion. In response to a boom in sex, drugs, and prostitution that earlier generations of communist leaders thought they had eradicated, Beijing is drafting a set of policies to battle AIDS. But the epidemic is more than a health problem in Beijing. Values on sexual morality, drug abuse, and human rights are being scrutinized as officials debate which is the best approach. Overseas experts insist the country should launch a large-scale campaign to educate the general public and to reach the groups at high risk with information, not punishment. With commercial sex and narcotics abuse subject to severe penal consequences and homosexuality barely acknowledged, there has been little discussion on how to reach these populations. Although promotion of medical and political rights for gays and drug users is abhorrent to China's leaders, it may nevertheless be critical in the fight to counter the AIDS threat. The issue is whether Beijing can find a way to deal with the "evils" of prostitution and drug abuse without stamping them out. One foreign expert says that trying to simply wipe them out will only drive AIDS underground and amplify the risk of infection. "An AIDS Risk That Can't Be Ignored" Boston Sunday Globe (11/28/93) P. A7 (Essex, Max) Max Essex, chairman of the Harvard AIDS Institute, predicts devastation and loss of lives will result if nations do not unite to battle HIV. Essex notes that in the 1990s there are new, more fierce strains of HIV emerging in Asia. By the turn of the century, he contends, that continent will have more infected people than the rest of the world combined. American and European corporations are scrambling furiously to develop an effective vaccine, but the lack of international corporate incentives is impeding the effort. The World Health Organization has listed several Asian and African countries as the most appropriate and efficient testing sites for these vaccines, for they experience the highest numbers of infections and have the greatest need. For vaccines to work in Africa and Asia, they must cater to the new strains that are most prevalent there, reasons Essex. Yet the trial vaccines have all been made with subtype B, which is dominant in America and Europe. Meanwhile, subtypes rampant in Asia and Africa--like the rapid and easily transmitted subtype F that is threatening Thailand--are left untested. Western corporations, who have the technology and expertise to develop treatments, hesitate to invest in vaccine research with strains from developing countries, claims Essex, because profits would be near non-existent and there would be pressure to make the vaccine accessible and affordable to those poor countries. The drug corporations are more eager to work with AIDS in the States, where profits may be high, even though efficacy would be hard to prove. "Safety Program Yielding Encouraging Results; Hypericin Used to Inactivate HIV in Blood" Business Wire (11/23/93) Stamford, Conn.--A program to develop hypericin, a antiviral compound that inactivates viruses in blood used for transfusions, is yielding promising results, according to an announcement by VIMRx Pharmaceuticals Inc. Studies at the NY Blood Center showed that hypericin achieved complete inactivation of infectious HIV in human blood. The dose of the compound necessary for inactivation leaves normal blood cells safe and does not interfere with standard blood tests. Scientists at VIMRx believe that hypericin should be an effective agent for protecting the blood supply. "Hypericin's unique mechanism of action targets free infectious virus before it has invaded a host cell and has begun to reproduce," explains Richard Podell, VIMRx president. "Hypericin can also prevent the transmission of active virus from an infected cell to an uninfected cell. We currently know of no other antiviral agent targeted for use with transfused blood that has demonstrated the in vitro effectiveness of hypericin and has a similar safety profile." Additional studies have shown that hypericin does not adversely affect normal blood chemistry, and is not toxic to major organs when administered intravenously. "Free 'AIDS in the Workplace' Seminar for Businesses Will Be Offered on World AIDS Day" PR Newswire (11/23/93) Los Angeles--United Way of Greater Los Angeles and the Press-Telegram will sponsor a free "AIDS in the Workplace" breakfast seminar on Dec. 1 in response to the increasing numbers of workers and businesses affected by the AIDS epidemic. The seminar, which coincides with World AIDS Day, will provide AIDS education and policy development information to business leaders and human resources personnel. Experts will present examples of company policies that address issues such as confidentiality of infected employees and the Americans with Disabilities Act. All participants will receive a comprehensive notebook of resource materials. Recent studies indicate that as much as 90 percent of the HIV population is in the workforce, and the increasing lifespan of infected people reflect the need for workplace education. "Portland Post Office Commemorates World AIDS Day With Wednesday, Dec. 1, Issuance of AIDS Awareness Stamps" PR Newswire (11/23/93) Portland--On Dec. 1, World AIDS Day, Portland Postmaster Michael Daley will host a ceremony recognizing the First Day of Issue for the new AIDS Awareness Stamp. Daley will be joined by Judith Hyde, a Portland letter carrier who walked nearly 3,000 miles across the country to spread her message of AIDS awareness to thousands of Americans. To close the ceremony, Daley and Hyde will unveil a large replica of the stamp design. They will then lead a symbolic walk as they help carry the two-foot by three-foot replica from the post office across the Broadway Bridge to Portland Memorial Coliseum. There, the enlarged stamp will be displayed with part of the AIDS Memorial Quilt. Attendees at the ceremony will also be able to obtain a special postmark for the stamp as a momento. "Internationally Renowned Talk Show Host Christina Saralegui Joins AmFar's National Council" PR Newswire (11/23/93) New York--World renowned print and broadcast personality Cristina Saralegui has accepted the invitation of the American Foundation for AIDS Research to join its national council. AmFar, established in 1985 by actress Elizabeth Taylor and scientist Dr. Mathilde Krim, is the premier private AIDS fundraising organization and a leader in AIDS research. The National Council includes more than 50 of the globe's most prestigious medical specialists, philanthropists, and celebrities including Rosalynn Carter, Phil Donahue, Jonas Salk and Barbara Streisand. The latest addition, Saralegui, is considered an influential force in the Hispanic community. In the business of journalism for a quarter of a century, she hosts her own international television talk show and radio programs and is co-publisher of her own international magazine. "I am confident that, with this new association, I will be able to bring important information to Hispanic men, women, and children in the U.S. and throughout the world about the dangers of AIDS--how it is spread and, most importantly, how to prevent it," said Saralegui. "I also hope to reach those already infected with the virus and to educate Hispanic people to be more accepting and supportive of those suffering with this dreaded disease." "The Liposome Company, Inc. Starts Phase III ABLC Trials in South Africa--Drug Being Tested in AIDS-Related Fungal Infections" PR Newswire (11/23/93) Princeton, N.J.--The Liposome Company, Inc. has begun clinical testing of its drug ABLC (amphotericin B lipid complex) in South African AIDS patients with cryptococcal meningitis, a fungal infection that occurs in as many as 10 percent of AIDS patients. The infection attacks the central nervous system, and 20 percent of patients die within a month of diagnosis. "Due to the AIDS epidemic in Africa, we believe we can efficiently conduct a larger Phase III study in cryptococcal meningitis in South Africa to confirm the efficacy and safety of ABLC," said Charles A. Baker, chairman and chief executive officer of Liposome. He added that the study will be conducted by 10 hospitals with large AIDS populations, and is slated for completion in 1994. The pharmaceutical company is also readying applications for approval to market the drug in Europe. It is already available on a compassionate use basis in America and Europe. ------- End of Forwarded Message