TI "Blessed With Resistance" AU Caldwell, Mark SO Discover (01/94) Vol. 15, No. 1, P. 46 AB Last June's international AIDS conference in Berlin yielded at best a grim outlook on the AIDS epidemic. In the absence of therapies and 100 percent effective preventive measures, the disease continues to spiral out of control and the World Health Organization predicts that some 40 million people will have AIDS by the turn of the century. Despite this gloomy forecast, the conference brought to light some glimmer of hope. A study of more than 1,500 female prostitutes in the slum area of Pumwani in Africa shows that a handful have demonstrated an apparent immunity to the AIDS virus despite innumerable exposures. Statistically, they should be infected, but are not. This study parallels U.S. studies of gay men who, despite high-risk sexual behavior, have remained virus-free and of infected patients who have managed to stave off illness for unusually long periods of time. These studies suggest that the immune systems of certain people are able to resist the virus, either by warding off infection completely or sharply curbing the progress of the disease. At a time when research on antiviral drugs and vaccines has failed, more researchers think perhaps it is time to explore what is most likely the nature of the immunity of HIV survivors: a hidden part of the immune system that is generally ignored. Copyright (c) 1993 - Information, Inc., Bethesda, MD. This information is provided by the Centers for Disease Control & Prevention (CDC), National AIDS Clearinghouse as a public service. Non-profit reproduction is encouraged. * Origin: AEGIS/San Juan Capistrano 714.248.2836 (CASAN) (1:103/927) * Provided as a service of THE BACKROOM - NYC * 718-951-8256